Save my name & email in this browser for the next Amylase deficiency is also known to trigger respiratory distress and contribute to asthma attacks. Serum amylase and/or lipase levels below the normal serum range are highly specific for chronic pancreatitis patients. Always keep digestive enzymes in mind, no matter what health issue your dog has. - Fast heartbeat. 2 0 obj Oozing sores on the skin. However, acute gastroenteritis has not been widely recognized as a cause for hyperamylasemia. Low levels indicate dietary imbalance, certain cancers, overdose of insulin, diabetes, eclampsia and an overactive parathyroid gland. Howell E.Food Enzymes for Health & Longevity. The top possible causes for this can be chronic inflammation, chronic infectious diseases, allergies and even cancer. The cPLI test should be considered for the following: Already have a myVCA account? Nutrients. In horses, serum ALP levels are highly variable, and are of limited diagnostic use . The liver produces bile, which is stored in the gallbladder. %PDF-1.5 Medications that might increase amylase level in your pet include metronidazole (Flagyl) and the diuretic, furosemide (Lasix). Low lipase levels are often considered normal because lipase can appear in the blood due to a damaged pancreas. <>>> What causes increased amylase and lipase in dogs? Sodium works in combination with potassium and is very important in maintaining normal function of muscle and nerves. BUN stands for blood urea nitrogen and is the primary end product of protein metabolism. How do you increase amylase levels in dogs? What would cause a dog to break out in hives? Most often it is associated with chronic protein loss due to an underlying disease. So the deficiency is compounded. liver disease. This cookie is set by GDPR Cookie Consent plugin. Pain medications are usually given by injection. Dogs at increased risk for pancreatitis, such as Miniature Schnauzers or dogs receiving potassium bromide anticonvulsant therapy. Pancreatitis can be quite variable in severity with some dogs not even requiring hospitalization. Hamburger meat can be purchased 96 percent lean, which will have the least amount of fat. Your pets blood amylase level can also be increased in pancreatic cancer or sudden severe trauma such as a car accident. When your dogs body absorbs nutrients better, hell benefit from better digestive health. A blocked intestine Lack of blood flow to the intestines Low levels of amylase in blood or urine are uncommon, but may be a sign of: Chronic pancreatitis causing permanent damage to the cells that make amylase Kidney disease Cystic fibrosis Liver disease Pre-eclampsia (a type of high blood pressure in pregnancy) A fasting sample is preferred, but it is not essential for the accuracy of the test. What causes high creatinine levels in dogs? That is because the compound has as very short lifespan. So if your dogs body makes all these digestive enzymes, why would he need supplements? But even your healthy dog could have a digestive enzyme deficiency. What causes low red blood cell count in dogs? Doc says he would like 290. Is ham toxic to dogs? For the first 24 hours, your vet may recommend no food or water, or may continue to give your pet food. Hi, Im Cara. Necessary cookies are absolutely essential for the website to function properly. Log in 24/7 to access your pets health care information. It is also an important electrolyte in every part of the body. The resulting fragments are completely hydrolyzed to p-nitrophenol and glucose by -glucosidase. Three of the dogs are rescue dogs, one dog is a full breed rescue, one is a full breed dog that comes from a line of raw fed dogs. The vet will most likely suggest this as well but its important to feed your dog a bland diet during the first one or two weeks of recovery. Heavy bleeding. An amylase test measures the amount of amylase in blood or urine (pee). This test measures the amount of amylase in the blood or urine or sometimes in peritoneal fluid, the fluid found between the membranes that cover the abdominal cavity and the outside of the abdominal organs. An amylase test measures the amount of amylase in blood or urine (pee). However, the serum value of amylase returned to within normal range earlier than the serum value of pancreatic lipase in 2 dogs; the reverse was true in 2 other dogs. Digestive enzymes are best given with food. Renal failure in dogs. High levels indicate dehydration, lack of water, diabetes insipidus, Cushings and excess salt intake. Microorganisms like bacteria and fungi create a protective layer called biofilm. I took her back for her blood test and her amylase level is now 152. The cPLI is currently considered the best blood test available for diagnosing pancreatitis in dogs. Follow the instructions on the label for correct dosing. This puts the pancreas and other organs of the endocrine system under tremendous stress, since they have to draw reserves from the entire body in order to produce massive amounts of the proper enzymes.. <> These include, Skin problems including eczema, psoriasis, allergic reactions, dermatitis, etc. But if the gallbladder doesnt produce enough bile, giving ox bile can provide it. 2002 Nov-Dec;35(5):391-397. After spending several years training dogs and people in a variety of environments, I formally earned my master dog training certificate. Your dog may need to be hospitalized for an acute pancreatitis attack. Your pets bloodlipase level, the pancreatic lipase immunoreactivity (TLI) test. Dogs with severe, sudden-onset pancreatitis are often very ill and show signs of vomiting, lethargy, loss of appetite, abdominal pain, and fever. excess protein in the urine shown by a urine test. Symptoms of Lack of Digestive Enzymes in Dogs Chronic diarrhea The signs of chronic pancreatitis include: When pancreatitis is chronic, thesesymptoms may come and go. An abnormal level of amylase can indicate a health problem, particularly a problem with the pancreas. What he meant, in plainer English, was that we use up the enzymes our bodies make. Chronic (long term) pancreatitis This is where the dog has developed problems over time, often with the symptoms building up gradually until eventually pancreatitis is diagnosed. He said as long as she is not exhibiting those symptoms she should be okay. Likewise, amylase is a non-specific enzyme that can be elevated in a variety of organ disorders, and even remain normal in dogs with documented . An increased BUN is called azotemia and can be caused by kidney, liver, or heart disease, urethral obstruction, shock, or dehydration. Should I put my dog down with pancreatitis? Additional causes include chronic infections, Crohn's disease, or malignant tumors. Some animals may be very severely ill with pancreatitis and will not recover despite treatment. that were in the raw ingredients. February 20, 2013. Watson P.Chronic pancreatitis in dogs. Hereditary disorders associated with fat metabolism. Units of measurement (link to conversion calculator), Sample type (serum, plasma, urine, body cavity fluids), Increased amylase activity (hyperamylasemia). Is pumpkin OK for dogs with pancreatitis? What do low levels of amylase and lipase mean? Dehydration and electrolyte (salt) imbalance causes affected dogs to be lethargic or weak. High levels indicate dehydration, inflammation, chronic infection and certain cancers. Medications that might increase amylase level in your pet include metronidazole (Flagyl) and the diuretic, furosemide (Lasix). Low levels indicate a basic condition of the blood and can be due to starvation, kidney failure (can also cause acidosis), diarrhea and poor liver function. o Ca (Calcium) - deviations can indicate a variety of diseases. These causes may include: Ox bile also helps control bacteria overgrowth. Biofilm can be a good thing. Especially in view of the highly processed diet that most of our pets are eating, this implies that most healthy adult dogs and cats can benefit from a digestive enzyme supplement. Phosphorus is often associated with calcium. Good Morning and welcome to Just answer. Low levels indicate vomiting and diarrhea, gastrointestinal cancer, insulin overdose, Cushings disease, overuse of diuretics and starvation. Dogs with less severe forms of pancreatitis may show only mild signs of illness, and some dogs may have low-grade ongoing problems with recurring episodes of illness. Interpreting Pancreatic Lipase (PL) Results in Dogs with a Balanced Overview Internal Medicine Acute pancreatitis is a common cause of vomiting, inappetence, lethargy and abdominal pain in dogs, but confidently diagnosing pancreatitis can be a challenge. span I comment. . Causes of Pancreatitis in Dogs Diet, particularly high fat diets. Tumors, hyperparathyroidism, kidney disease, and low albumin are just a few of the conditions that alter . The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. Join nearly 100,000 subscribers who love Dogs Naturally to unlock special discounts and premium content. What does a low amylase level mean? A Short Caution About Being Your Own Veterinarian. However, the changes are not unique to the disease and do not give a definitive diagnosis. Yes, a dog that is suffering from pancreatitis might drink a lot of water, which can actually help him. Are scrambled eggs good for dogs with pancreatitis? PetPlace may be compensated when you click on or make a purchase using the links in this article. Potassium works in combination with sodium and is very important in maintaining normal function of muscle and nerves. . In dogs with low levels of albumin (hypoalbuminemia), the biochemistry profile will show levels of albumin and disturbances in calcium levels. (One strange bit of trivia is that invertase is used in the candy industry to make chocolates with fondant fillings!). In cats, alendronate is the most common oral preparation used to control idiopathic hypercalcemia. Digestive Enzymes. My love for dogs began at the age of 4 when my first family pet was a black lab named Dallas who was most definitely not trained to do tricks! Neutropenia is a decrease in the number of neutrophils in the bloodstream. In healthy dogs, 14% of amylase is bound to globulins. New Jersey: Avery Publishing Group, 1985. High levels indicate certain forms of cancer, Addisons disease, excess intake of vitamin D and an overactive parathyroid gland. BUN (blood urea nitrogen)..24 mg/dl(8-29) Low levels indicate vomiting and diarrhea, gastrointestinal cancer, insulin overdose, Cushing's disease, overuse of diuretics and starvation. Malabsorption of nutrients. What Brand Of Peanut Butter Is Best For Keto? Xiu-an Zhan et al. Infection of the salivary glands (mumps). This will help confirm the diagnosis of pancreatitis and provide a starting point or baseline that can be used to monitor the pets progress after treatment has been started. AST is important in the breakdown and elimination of nitrogen. Low levels can indicate malnutrition or starvation. 2001 Sep;183(18):5385-5394. Having a lower than normal ALT result is uncommon and usually isn't a cause for concern. If an amylase test finds too much amylase in your blood or urine, it may indicate a pancreas disorder or other health condition. Bilirubin is a bile pigment and is the end product of red blood cell breakdown. These include excessive thirst, frequent urination, extreme tiredness (fatigue), and weight loss. Twenty of the most common tests are listed. Familial Lipoprotein Lipase Deficiency People with no lipase in their blood may have familial lipoprotein lipase deficiency, a rare genetic disorder that causes colic in infants as well as nausea and pain in the muscles, bones and . Eggs are a good source of protein. If the pancreas isnt working properly, its not going to produce the digestive enzymes your dog needs. Pamidronate is the most commonly used parenteral drug; the recommended dosage in dogs is 1-2 mg/kg, IV, mixed in 0.9% saline given throughout 2 hr. Digestive enzymes can be used for pancreatic and GI issues, but are also beneficial for healthy patients eating heat-processed pet foods., recent research shows that in humans with gastrointestinal disease, but more importantly, even in normal individuals, supplementation with digestive enzymes substantially increased digestion in the lumen of the small intestine, and improved the bioavailability of proteins and carbohydrates. Active enzyme does not appear in urine. High levels indicate bile duct obstruction, liver disease, pancreatitis, Cushings and can be caused by high levels of steroids. American Journey Healthy Weight Chicken and Sweet Potato Recipe. It separates sugar into glucose and fructose, which helps with digestion of starchy carbohydrates. When the pancreas is damaged, these digestive enzymes can be found in the blood at higher levels than normal. Can dogs recover from pancreatitis on their own? - pancreatic cysts or sores. The concentration of amylase is measured in U/L (conventional units) andkat/L (SI units). Meats high in fat such as lamb and pork should be avoided. Copyright 1999 - 2023. Pancreas specific enzymes: Classically, elevations in serum amylase and lipase activity have been used as indicators of pancreatic inflammation in dogs. Thus, whats left of the food mass enters the small intestine largely undigested. Severe gastroenteritis Perforated ulcer. Have you considered giving digestive enzymes to your dog? One reason for an enzyme deficiency is your dogs diet. What is a normal amylase level for a dog? First,the pancreas creates most of the digestive enzymes your dog needs. Betaine HCL boosts production of hydrochloric acid in the stomach. Bisphosphonates assist in lowering serum calcium by reducing the number and action of osteoclasts. Your email address will not be published. A pancreas-specific lipaseis a form of lipase produced only in the pancreas. If you enjoy the site, please support our mission and consider a small gift to help us keep pace with its rapid growth. Edward J Hall MA VetMB PhD DECVIM-CA. In the meantime, feed your dog a healthy diet and keep him lean. 2022 - Dogs Naturally Magazine Inc. Can amylase be elevated without pancreatitis? RELATED: Read more detail about pancreatitis in dogs . Pancreatitis, tumors, gallbladder infections, kidney infections, and the use of certain medications are all common causes of increased amylase levels. He asked about appetite, bowels, and if she is vomiting. Lack of digestive enzymes in dogs is a condition in which the pancreas no longer produces enough enzymes to properly digest food, which means that food often passes through the digestive tract of dogs undigested, leading to extreme weight loss and malnourishment. Villaverde C, Manzanilla EG, Molina J, Larsen JA. PapainPapain is the enzyme contained in papaya fruit. Many dog owners want to know if eggs are an acceptable food to offer dogs with pancreatitis. J Bacteriol. Innovative Veterinary Care. 222-232 (68 ref.). And papain is anti-parasitic, so can help your dog eliminate worms. or hemolyzed samples (= red blood cells damaged during collection) can result in a falsely elevated amylase reading. How Long Can dogs live with pancreatitis? And to make matters worse, as your dog ages his body produces fewer enzymes naturally. She's on the Board of Playing Again Sams (Wisconsin Samoyed Rescue) where she enjoys helping adopters and group members choose natural health care options for their dogs. In dogs, the higher the serum amylase activity (3 to 4 fold increase), the more likely the presence of pancreatic disease. Calcium (Ca): Changes in the normal level of this test can indicate a variety of diseases. However, with severe or repeated episodes of pancreatitis, one or more of the following problems may develop: If a significant number of cells that produce digestive enzymes are destroyed, a lack of proper food digestion may follow. In dogs, glucocorticoids (endogenous or exogenous) induce an isoenzyme in the liver (C -ALP) that contributes to serum increases In cats, the hepatic isoenzyme has such a short half life that even minor increases are considered significant. Antiemetic medication for vomiting (to prevent dehydration), Resting the pancreas (withholding food and water for 24 hours). It is important in all aspects of metabolism. Low serum amylase is also associated with insulin deficiency in patients with type 1 diabetes and, less commonly, with type 2 diabetes [1013], as well as the pathogenesis of insulin resistance in obese animal models [14, 15]. How do I know if my dog has an electrolyte imbalance? You can add a little water or broth if needed. So how can you tell your dog needs more digestive enzymes? Chloride.104 mEq/l(10-118) Sodium (Na).140 mEq/l(139-164) What can cause elevated kidney levels in dogs? Low Levels Commonly diagnosed conditions associated with low lipase levels in dogs include diabetes, high cholesterol levels, high blood pressure levels, vitamin deficiency, pancreatitis, kidney diseases, fatty liver disease and other such health conditions that are caused by reduced digestion of fats. Some of the most common causes of the syndrome include: Liver failure: The liver manufactures albumin. Studies have demonstrated that cPLI has a high degree of accuracy in diagnosing canine pancreatitis. Neutrophilia is an increase in the number of neutrophils in the bloodstream and is caused by inflammation. The cookie is used to store the user consent for the cookies in the category "Analytics". Top Companion Anim Med. The four dogs live in Washington State, New York, and Florida. Low levels Summary An amylase blood test measures the amount of amylase in a person's blood. He found that the lack of enzymes from cooked food causes shortened life span in people and animals, due to . If youve wondered Can dogs eat ham?, the answer is no. Chronic pancreatitis is most often caused by heavy alcohol use. Typically with pancreatitis, I will see amylase increase in value and not decrease but it does not always follow that rule. Low levels indicate starvation, severe diarrhea, vomiting, Addisons disease, hypothyroidism and metabolic acidosis. Low levels indicate chronic inflammation, liver disease, kidney disease, starvation and blood loss. A range of health issues can cause hypoalbuminemia. Low levels indicate vomiting and diarrhea, gastrointestinal cancer, insulin overdose, Cushing's disease, overuse of diuretics and starvation. Your dog shouldnt have any side effects other than improved digestion! So here are some facts about digestive enzymes for dogs and when to use them. Cellulase has another benefit: it helpscontrol blood sugar levels. Liver disease. Veterinarian Dr PJ Broadfoot said in a 2018 paper: Supplemental enzymes are needed to replace those destroyed by cooking and processing food. Most cases in dogs are caused by pancreatic acinar atrophy, though some may also develop because of chronic . . Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. Posted by Dr. Michael Richards. Food microstructure affects the bioavailability of several nutrients. Besides just using up his own enzyme supply your dog might have a specific health issue that these supplements can help with. You can donate securely via PayPal or credit card. You may also notice pain in the middle of your chest, which may move or radiate to your back. High levels indicate dehydration. But if he gets any gas or loose stools at first, just reduce the dose a little until his body adjusts to the new digestive support. If your dog eats food with starchy ingredients (like kibble and even some canned, freeze dried or dehydrated foods) he may not produce enough enzymes to break it down. Dogs with less severe forms of pancreatitis may show only mild signs of illness, and some dogs may have low-grade ongoing problems with recurring episodes of illness. Never cook it as heat will destroy the enzymes. High levels indicate an acidic condition and can be due to kidney failure, vomiting, dehydration or overuse of diuretics. Processing and cookingatany heat of approximately 118F to 129F (48C to 54C), for as few as three minutes, can destroy virtually all enzymes,which results in very little pre-digestion taking place in the stomach. Creatine phosphokinase (CPK) or creatinine kinase (CK) value elevations. Digestive Enzymes In Dogs And Cats. He gave me a supplement powder "Prozyme" to add to her food twice a day and asked me to bring her back for an additional blood test in 3 weeks. Blue Buffalo Life Protection Formula Healthy Weight Dog Food for Pancreatitis. Injury of pancreatic acinar cells (most commonly from pancreatitis) may increase serum amylase, and about 60% of dogs with renal failure also have increased levels. It is stable in urine for 10 days at 2 8 C, or 2 days at 20 25 C. Your dogs body cant keep up! So eventually we deplete our enzyme resources, which shortens our lives. What causes high amylase levels in dogs? Yeast cell walls are made of cellulose. Triglyceride is important in storing fat and releasing fatty acids. That is because the compound has as very short lifespan. Symptoms Of Digestive Enzyme DeficiencyWatch for these signs your dog may need some digestive enzyme support: If you recognize your dog in these symptoms, digestive enzymes could make a big difference! This type of probiotic forms spores that will help the probiotics arrive intact at the large intestine and colon so they wont feed the bacteria in the small intestine like other probiotics. So cellulase can help break down the cellulose and remove the yeasts defenses. Buy Digest now >>. Chronic liver disease is the most common cause of high bilirubin levels in dogs and cats. Creatinine.0.8 mg/dl(0.4-1.2) Because the blood amylase level can fluctuate so widely, the significance of the value your veterinarian obtains in a single test can be quite hard for him/her to interpret. The gallbladder releases bile after a meal, to break down fats into fatty acids for digestion. Additional testing may include further blood tests, a urine test, and an ultrasound or CAT scan of your abdomen. Dogs with severe pancreatitis have somewhere around a 33% death rate within 30 days of being admitted to a referral hospital. Meanwhile, if alkalosis is a cause of hypocalcemia, the blood gas analysis will reveal abnormally high levels of . So, after 2-3 days, the level of ALT that has increased due to hepatic injury starts to decrease. GGT is also important in nitrogen metabolism and is found within liver cells. Enzyme Deficiency Affects The Whole BodySo even your healthy dog can deplete his own digestive enzyme sources. Exocrine pancreatic insufficiency (EPI) is a condition in which the pancreas no longer produces adequate amounts of digestive enzymes. Vigorous monitoring of a worsening condition. P-amylase in the blood increases when the pancreas is inflamed or damaged. The half-life of the ALT enzyme is short. Make sure you are hydrated (unless instructed otherwise). Serum Amylase and Lipase Activities. Use treats and a gentle voice to lead your dog away from the area. High levels indicate muscle trauma or damage such as due to seizures, surgery, bruises, inflammation, nutritional and degenerative diseases. . Lipemic (fatty) blood samples (a recent meal?) And if your dog has EPI, its best to moisten any pancreatic enzymes you give. Here are some chronic health issues that need extra digestive enzyme support. Some people call ox bilethe ultimate digestive enzyme. Elevated levels can indicate pancreatitis or renal damage. The increased use of food enzymes promotes a decreased rate of exhaustion of the enzyme potential.. Since then I have had several dogs ranging from pugs to Dobermans and I have an unreasonable enthusiasm for all things doable or teachable in dog training. Merck Veterinary Manual, June 2020. The way you feed and raise your dog creates some situations where digestive enzymes can really help your dog. Its important for digestive health. CO2 (carbon dioxide).22 mEq/l(22-285) What causes elevated BUN levels in dogs? By Wang, H.; Li, S.; Fang, S.; Yang, X.; Feng, J.Betaine Improves Intestinal Functions by Enhancing Digestive Enzymes, Ameliorating Intestinal Morphology, and Enriching Intestinal Microbiota in High-salt stressed Rats. In some dogs with pancreatitis, amylase and lipase enzymes are also found to be elevated. Your vet can diagnose EPI using a test called TLI trypsin-like immunoreactivity test. Injury of pancreatic acinar cells (most commonly from pancreatitis) may increase serum amylase, and about 60% of dogs with renal failure also have increased levels. Hi there and thank you for using PetCoach to address your concern. What Are Digestive Enzymes?Your dog naturally produces digestive enzymes in his body. Causes of Low Body Temperature Temperatures that are lower than 98 degrees may indicate that something's wrong. Howell E.Enzyme Nutrition: The Food Enzyme Concept. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. In light of this, what does low amylase mean?. In fact, your dog likely needs help absorbing nutrients from the food he eats. Papain is used in medicine to treat pain and inflammation. Sadly in these cases euthanasia may be the kindest option to prevent suffering.. For milder cases, your dog will need to be in the hospital anywhere from 2 to 4 days. The pancreas is the organ that produces most digestive enzymes in your dog, so feeding pancreas supports and fortifies the pancreas. These patients can die from a severe whole-body inflammatory condition, which results in multiple organ failure. This enzyme is sensitive for hepatobiliary disease in dogs (80%), but because of the possible contributions of bone and glucocorticoid-induced isoenzymes to serum ALP activity, its specificity is low (51%). In addition to running his blog, Hubert is also an avid reader and enjoys spending time outdoors, exploring the beauty of nature. CO2 indicates the current acid balance of the body and is the end product of metabolism. Antibiotics. Thus, when the patient experiences diarrhea, fever, vomiting, indigestion, or jaundice, he should contact the healthcare provider. - Pain in your upper abdomen (belly) that may spread to your back or get worse after eating. Amylase..850 U/l(280-950) Ox BileRemember earlier we said the gallbladder as an important part of your dogs digestive system? That condition causes the liver to produce too much cholesterol, which then makes its way to the bloodstream. Low amylase levels can indicate: Chronic pancreatitis, an inflammation of the pancreas that gets worse over time and can cause permanent damage.Chronic pancreatitis is most commonly caused by heavy alcohol consumption. Large muscle mass may explain moderately increased blood creatinine concentration. After studying at Madrid University in Spain, she spent 35 years in international banking before joining Dogs Naturally Magazine in 2010. A biochemical profile, commonly also referred to as the blood profile or blood chemistry, is a blood test commonly done in dogs that assesses the function of internal organs, measures the electrolytes such as blood potassium, and identifies the levels of circulating enzymes. Dogs that get into garbage can develop pancreatitis. Tumors, hyperparathyroidism, kidney disease, and low albumin are just a few of the conditions that alter serum calcium Cholesterol (CHOL): This test is used to supplement diagnosis of hypothyroidism, liver disease, Cushing's disease and diabetes mellitus A rapidly falling cPLI value, together with improvement in the dog's condition, indicates a good response to treatment. When pancreatitis is suspected in a dog or a cat such as one with a tender or bloated abdomen, an abdominal fluid tap (withdrawal) from its tummy is more likely to have a higher amylase reading than the reading obtained from the blood of the same pet. It is highly specific to the pancreas, and blood values increase only when pancreatic inflammation occurs. But opting out of some of these cookies may affect your browsing experience. Lab Appointments & Locations A normal lipase level can range from 0 to 160 U/L depending on the lab. The increased amylase seen in dogs with conditions associated with decreased GFR (pre-renal, renal, post-renal azotemia) may be due to macroamylase formation. Symptoms of pancreatitis may include nausea, sweating and weakness. Parada J, Aguilera JM. The half-life of amylase (as determined from sequential decreases in sick horses over time) appears to be around 4 0.7 hours in horses, which is shorter than that of lipase (approximately 11 hours) (Johnson et al 2019).

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